OCT-Measured Plaque Free Wall Angle is Indicative for Plaque Burden: A New Decision Tool for Determining The Optimal Stent-Landing Zone

The aim of this study was to investigate the relationship between the plaque free wall (PFW) measured in OCT and the plaque burden (PB) measured in IVUS which could be used as a new decision tool to determine the optimal stent-landing zone with a PB<40%.

There is a significant non-linear relationship between PFWOCT and PBIVUS (r2=0.59). The optimal cut-off value of the PFWOCT for the prediction of a PBIVUS<40% is ≥220° with a specificity of 78% and an NPV of 88%. This indicates that when the PFWOCT is ≥220°, in 78% of the cases, the PB is <40%, representing an optimal stent-landing zone.

This study shows for the first time that PFW angle in OCT can be considered as a surrogate marker for PB, which is currently a common criterion to determine stent-landing zone.

OCT-Measured Plaque Free Wall Angle