Automated Characterization of Lipid-Core Plaques in Vivo by Quantitative Optical Coherence Tomography Tissue Type Imaging

The purpose of this study was to validate optical coherence tomography (OCT) attenuation imaging for tissue characterization in vivo, specifically to detect lipid core in coronary atherosclerotic plaques as assessed by near-infrared spectroscopy and intravascular ultrasound (NIRS-IVUS), and to quantitatively evaluate the ability of OCT attenuation imaging to differentiate thin-cap (TCFA) and thick-cap fibroatheroma (FA).

Automated Characterization of Lipid Core Plaques